1、軟組織梭形細胞肉瘤有什麼最好治療辦法?希望有知道的朋友幫幫忙?
顯然首要是要用手術治療,且手術要盡可能切除干凈,這樣復發幾率小,其次可以考慮應用化療葯物,防止血道轉移,一般來講,軟組織肉瘤預後和腫瘤分化有明顯關系。
2、【右髂骨】梭形細胞軟組織腫瘤【考慮侵襲性纖維瘤】是否可以手術?謝謝【【右髂骨】梭形細胞軟組織腫瘤】
從MRI上應該能看到腫物的大小及與骨的關系,建議如果能夠手術就一定要手術。可到骨科就診
(北京協和醫院邵亞娟大夫鄭重提醒:因不能面診患者,無法全面了解病情,以上建議僅供參考,具體診療請一定到醫院在醫生指導下進行!)
3、求高手翻譯一篇英語論文!!!!!!!!
Cytology of soft tissue tumors: Cytological classification of soft tissue tumors
有關軟組織腫瘤的細胞學:軟組織腫瘤在細胞學上的分類
Manoj Kumar Choudhuri (名字)
Department of Pathology, B S Medical College, Bankura, West Bengal, India
BS醫學院,病理學系,印度西孟加拉Bankura
Depending on existing knowledge, classification of any disease changes from time to time, as is the case with soft tissue tumors. The WHO classification of soft tissue tumors was first published in 1969 and was revised twice in 1994 and 2002.
根據現存的知識,對於」疾病的變化」所做的分類,一直隨時間在改變。對軟組織腫瘤所做的分類就是這樣一個例子。世界衛生組織(WHO)對軟組織腫瘤所做的分類,最先發表於1969年,並分別於1994與2002年做過修訂。
Following are some of the major changes that have taken place in the latest classification: [1],[2]
以下是」最新分類』上出現的一些主要改變。
Fibroblastic tumor / so-called fibrohistiocytic tumor : The most striking change in this group is that malignant fibrous histiocytoma has lost its glory and has been relegated to an "undifferentiated pleomorphic sarcoma." Myxoid fibrous histiocytoma has been replaced with "myxofibrosarcoma," which represents the most common soft tissue sarcoma in elderly indivials.
纖維組織母細胞腫瘤/即所謂的纖維組繊球性腫瘤(fibrohistiocytic tumor):
這個群組最顯著的改變在於,惡性纖維所構成的組織細胞瘤已經不像過去那樣意義非凡,現已被貶為一種」未分化多形性肉瘤(undifferentiated pleomorphic sarcoma)」。 粘液樣纖維構成的組織細胞瘤(myxoid fibrous histiocytoma)已經被黏液纖維肉瘤(myxofibrosarcoma)所取代,這是老年人最常見的軟組織肉瘤。
Smooth muscle tumor and skeletal muscle tumors : There has been no significant change in this group.
平滑肌腫瘤與骨骼肌腫瘤:這個群組並未有明顯的改變。
Adipocytic tumors : A well differentiated liposarcoma has no malignant potential, thus, "atypical lipomatous tumor" is the preferred term when the tumors arise at extremities and other surgically amenable sites. However, the term, "well differentiated liposarcoma" is reserved for tumors arising in the retroperitoneum and mediastinum. Incomplete resection results in local recurrence even in the absence of dedifferentiation. Myolipoma and chondroid lipoma are two new entities included in the recent classification.
脂肪細胞腫瘤:是一種不具惡性潛能的分化良好型脂肪肉瘤,因此,不典型脂肪瘤樣腫瘤(atypical lipomatous tumor)這個名稱被採用,因為腫瘤發生在身體末端如四肢,以及其它適合外科手術的地方。然而,分化良好型脂肪肉瘤(well differentiated liposarcoma)這個名稱,則是被用於發生在後腹腔與縱膈腔的腫瘤。即使在沒有」失分化」的情況下,切除不完整將導致局部性再發。肌脂瘤(myolipoma)與軟骨樣脂肪瘤(chondroid lipoma)是新加入分類中的兩個種類。
Pericytic tumors : Some tumors previously categorized as hemangiopericytomas are indistinguishable from "solitary fibrous tumors." However, sinonasal hemangiopericytomas appear to be truly pericytic lesions. Large groups of pericytic / perivascular tumors have been renamed as "myopericytomas".
周細胞腫瘤:一些先前被歸類為血管外皮細胞瘤(hemangiopericytoma)的腫瘤,與孤立性纖維性腫瘤(solitary fibrous tumor)的區分不是很明顯。然而,鼻腔鼻竇血管外皮細胞瘤(sinonasal emangiopericytomas)看似真正周細胞的損害。
周細胞的大群組已被更名為肌周細胞瘤(myopericytomas)。
Vascular tumors : Spindle cell haemangioendotheliomas have been renamed as "spindle cell hemangiomas."
血管腫瘤:紡錘體細胞血管內皮瘤(Spindle cell haemangioendothelioma)已被更名為紡錘體細胞血管瘤(spindle cell hemangiomas)。
All of us appreciate that diagnosis by fine needle aspiration depends on pattern recognition. Thus, cytological classification of soft tissue tumors is based on the principal pattern. Immunocytochemistry has been increasingly used in the recent past for further categorization of the lesions.
藉細針吸取所做的診斷,是依賴於對形態(pattern)的辨識。因此,細胞學對軟組織腫瘤的分類,就是根據」主要形態」(pattern)所建立的。免疫細胞化學於最近已經逐漸被使用在更進一步的器官損害之范疇內。
Soft tissue tumors are classified into five groups [3] on the basis of their cytological results:
根據細胞學上的結果,軟組織腫瘤被分為五個群組:
Pleomorphic pattern : The aspirate is richly cellular and there is a marked variation in cell size and shape. Nuclear pleomorphism is striking and some of the tumor cells show large nucleoli; bizzare tumor giant cells can be detected. Pleomorphic liposarcomas, pleomorphic undifferentiated sarcomas, and pleomorphic rhabdomyosarcomas belong to this group.
多形性形態:抽吸(aspirate)完全是細胞的,並且在細胞尺寸與形狀上有非常大的差異。細胞核多形性很突出,並且有些腫瘤細胞顯示有大細胞核;可偵測到怪異腫瘤巨大細胞。多形性脂肪肉瘤,多形性未分化肉瘤以及多形性橫紋肌肉瘤都屬於這個群組。
Spindle cell pattern : Spindle cells are shed as fascicles. A typical spindle cell has fusiform or ovoid nuclei; the cytoplasm is tapered, unipolar, or bipolar; mitotic figures are variable. Fibrosarcomas and leiomyosarcomas present with this classical spindle cell pattern.
紡錘體細胞形態:紡錘體細胞褪為叢團。典型的紡錘細胞呈紡綻狀,或者卵圓形細胞核。該細胞質一端寬一端較細,單極的,或雙極的;有絲分裂的外觀是易變的。纖維肉瘤與子宮肌肉瘤出現典形的紡錘細胞形態。
4、什麼是梭形軟組織腫瘤?
梭形軟組織腫瘤主要是以梭形細胞為主,可發生在任何器官或組織,形態學表現可以是癌也可以是瘤。如發生在上皮組織(如梭形細胞癌、梭形細胞鱗癌),也可以發生在間葉組織(如梭形細胞肉瘤,梭形細胞間質肉瘤),形態表現復雜,多類似肉瘤,或伴有形似肉瘤的間質成份,免疫表型既可表現為癌,也可表現為肉瘤,或表現為癌肉瘤結構等的一類腫瘤。該病變較難直接檢查,需多方面的檢測如免疫組織化學標記等。